Cisplatin-conjugated gold nanoparticles as a theranostic agent for head and neck cancer.

BACKGROUND The purpose of this study was to develop a nanoplatform, which simultaneously acts as radiosensitizer, drug carrier, and tumor imaging agent for head and neck cancer. METHODS We synthesized 20 nm gold nanoparticles, coated with glucose and cisplatin (CG-GNPs). Their penetration into tumor cells and their cellular toxicity were evaluated in… CONTINUE READING