Cisplatin-based combination chemotherapy for disseminated germ cell tumors: long-term follow-up.

@article{Roth1988CisplatinbasedCC,
  title={Cisplatin-based combination chemotherapy for disseminated germ cell tumors: long-term follow-up.},
  author={Bruce J. Roth and Anne Greist and Paul S. Kubilis and Stephen D. Williams and Lawrence Henry Einhorn},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1988},
  volume={6 8},
  pages={1239-47}
}
A retrospective analysis of the initial 229 cases of disseminated germ cell tumors treated at Indiana University with cisplatin, vinblastine, and bleomycin (PVB), with or without doxorubicin revealed 146 patients who are alive and disease-free with a minimum follow-up of 6 years and a median follow-up of 8.5 years. At 12 years, the estimated probability of survival is 65.0%, and the estimated probability of relapse-free survival for complete responders is 83.5%. Long-term complications, such as… CONTINUE READING