Cis-regulatory elements of the mitotic regulator, string/Cdc25.

@article{Lehman1999CisregulatoryEO,
  title={Cis-regulatory elements of the mitotic regulator, string/Cdc25.},
  author={Dara A. Lehman and Briony Patterson and Laura A Johnston and Tanja Balzer and Jessica S Britton and Robert E. Saint and Bruce A Edgar},
  journal={Development},
  year={1999},
  volume={126 9},
  pages={1793-803}
}
Mitosis in most Drosophila cells is triggered by brief bursts of transcription of string (stg), a Cdc25-type phosphatase that activates the mitotic kinase, Cdk1 (Cdc2). To understand how string transcription is regulated, we analyzed the expression of string-lacZ reporter genes covering approximately 40 kb of the string locus. We also tested protein coding fragments of the string locus of 6 kb to 31.6 kb for their ability to complement loss of string function in embryos and imaginal discs. A… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 55 references

Cell cycling and patterned cell proliferation in the wing primordium of Drosophila.

Proceedings of the National Academy of Sciences of the United States of America • 1996

Similar Papers

Loading similar papers…