Cis‐Regulatory Elements Controlling Basal and Inducible VIP Gene Transcription

  title={Cis‐Regulatory Elements Controlling Basal and Inducible VIP Gene Transcription},
  author={Sung Ho Hahm and Lee E. Eiden},
  journal={Annals of the New York Academy of Sciences},
  • S. H. Hahm, L. Eiden
  • Published 1 December 1998
  • Biology
  • Annals of the New York Academy of Sciences
Abstract: The cis‐acting elements of the VIP gene important for basal and stimulated transcription have been studied by transfection of VIP‐reporter gene constructs into distinct human neuroblastoma cell lines in which VIP transcription is constitutively high, or can be induced to high levels by protein kinase stimulation. The 5.2 kb flanking sequence of the VIP gene conferring correct basal and inducible VIP gene expression onto a reporter gene in these cell lines was systematically deleted to… 

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