Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance.

  title={Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance.},
  author={Agust{\'i}n Albillos and Margaret Lario and Melchor {\'A}lvarez-Mon},
  journal={Journal of hepatology},
  volume={61 6},
The term cirrhosis-associated immune dysfunction refers to the main syndromic abnormalities of immune function, immunodeficiency and systemic inflammation that are present in cirrhosis. The course of advanced cirrhosis, regardless of its aetiology, is complicated by cirrhosis-associated immune dysfunction and this constitutes the pathophysiological hallmark of an increased susceptibility to bacterial infection, distinctive of the disease. Cirrhosis impairs the homeostatic role of the liver in… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 134 references

Cardiac and proinflammatory markers predict prognosis in cirrhosis.

Liver international : official journal of the International Association for the Study of the Liver • 2014
View 4 Excerpts
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Immune surveillance by the liver

Nature Immunology • 2013
View 3 Excerpts
Highly Influenced

Adhesion molecules as a prognostic marker of liver cirrhosis.

Scandinavian journal of gastroenterology • 2005
View 5 Excerpts
Highly Influenced

Tumour necrosis factor-alpha expression by activated monocytes and altered T-cell homeostasis in ascitic alcoholic cirrhosis: amelioration with norfloxacin

A Albillos, L Hera Ad Ade, +3 authors M Nieto
J Hepatol 2004;40:624–631 • 2004
View 17 Excerpts
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