Corpus ID: 9432839

Cirrhosis and chronic liver failure: part I. Diagnosis and evaluation.

@article{Heidelbaugh2006CirrhosisAC,
  title={Cirrhosis and chronic liver failure: part I. Diagnosis and evaluation.},
  author={Joel J. Heidelbaugh and Michael Bruderly},
  journal={American family physician},
  year={2006},
  volume={74 5},
  pages={
          756-62
        }
}
Cirrhosis and chronic liver failure are leading causes of morbidity and mortality in the United States, with the majority of preventable cases attributed to excessive alcohol consumption, viral hepatitis, or nonalcoholic fatty liver disease. Cirrhosis often is an indolent disease; most patients remain asymptomatic until the occurrence of decompensation, characterized by ascites, spontaneous bacterial peritonitis, hepatic encephalopathy, or variceal bleeding from portal hypertension. Physical… Expand
Cirrhosis: Diagnosis and Management.
TLDR
Screening tests to assess fibrosis include the aspartate transaminase to platelet ratio index score, Fibrosis 4 score, fibroTest/FibroSure, nonalcoholic fatty liver fibrosis score, standard ultrasonography, and transient elastography, which are most useful in identifying patients with no to minimal fibrosis or advanced fibrosis. Expand
Cirrhosis: diagnosis, management, and prevention.
TLDR
Treating alcohol abuse, screening for viral hepatitis, and controlling risk factors for nonalcoholic fatty liver disease are mechanisms by which the primary care physician can reduce the incidence of cirrhosis. Expand
Cirrhosis and chronic liver failure: part II. Complications and treatment.
TLDR
Survival rates in transplant recipients have improved as a result of advances in immunosuppression and proper risk stratification using the Model for End-Stage Liver Disease and Child-Turcotte-Pugh scoring systems. Expand
The Role of Liver Transplantation in Alcoholic Hepatitis
TLDR
It is demonstrated that early liver transplantation in carefully selected patients with severe alcoholic hepatitis who fail medical therapy can provide a significant survival benefit and yields survival outcomes comparable to liver transplants for other indications, with 6-month survival rates ranging from 77% to 100%. Expand
Presentation and complications associated with cirrhosis of the liver
  • F. Poordad
  • Medicine
  • Current medical research and opinion
  • 2015
TLDR
Although substantial progress has been made to prevent the complications and mortality associated with Cirrhosis, liver transplantation in combination with resolution of the etiology of cirrhosis remains the only curative option for most patients. Expand
CASE STUDY OF PATIENT WITH LIVER CIRRHOSIS
TLDR
The hepatologist recommended liver transplantation as the last resort for an Asian man who was the victim of liver cirrhosis that was complicated by untreated hepatitis c. Expand
Diagnostic Accuracy of Non-invasive Laboratory-Based Fibrosis Scores in Predicting the Presence of Esophageal Varices in Liver Cirrhosis
TLDR
Early diagnosis of varices and primary prophylaxis of variceal bleeding in high-risk patients with liver cirrhosis is important in improving survival. Expand
The etiology of hepatocellular carcinoma and consequences for treatment.
TLDR
There are still many gaps in current understanding, and further research efforts are needed to fully elucidate the diverse mechanisms involved in the pathogenesis of HCC and offer optimal prevention strategies for those at risk. Expand
Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients
TLDR
Chronic PPI use in cirrhotic patients is associated with significantly higher average West Haven Criteria for HE compared to patients that do not use PPIs. Expand
Liver function tests in chronic viral hepatitis cases
TLDR
Screening for the chronic hepatic injury is not cost-effective and should be limited to high-riskindividuals, and ALT should be the preferred biochemistry parameter besides viral serology and increased activity should be confirmed before further evaluation. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 28 REFERENCES
Cirrhosis and chronic liver failure: part II. Complications and treatment.
TLDR
Survival rates in transplant recipients have improved as a result of advances in immunosuppression and proper risk stratification using the Model for End-Stage Liver Disease and Child-Turcotte-Pugh scoring systems. Expand
Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology.
TLDR
The finding of abnormal liver function tests in the absence of diagnostic serology may indicate significant liver disease. Expand
Reversibility of cirrhosis in chronic hepatitis B.
TLDR
Cirrhosis due to chronic hepatitis B might be reversible in some patients who respond to antiviral therapy, and this work is the first to suggest this possibility. Expand
Non-invasive diagnosis of esophageal varices in chronic liver diseases.
TLDR
The results show that the non-invasive screening of patients who are candidates for the primary prevention of variceal bleeding is possible, but should be improved before being used in a clinical setting. Expand
Diagnosis and Monitoring of Hepatic Injury. II. Recommendations for Use of Laboratory Tests in Screening, Diagnosis, and Monitoring
TLDR
Although ALT is useful for detecting acute and chronic hepatic injury, it is not related to severity of acute Hepatitis B and C and only weakly related to severe severity of chronic hepatics injury. Expand
Viral-induced cirrhosis: grading of severity using MR imaging.
TLDR
An MR scoring system can be used to grade the severity of cirrhosis and volume indexes of the posterior, medial, and lateral segments of the liver were significantly and inversely correlated. Expand
Relation of hemochromatosis with hepatocellular carcinoma: epidemiology, natural history, pathophysiology, screening, treatment, and prevention.
TLDR
With increasing clinical recognition, hemochromatosis should be diagnosed earlier and progression to cirrhosis and HCC should be minimized. Expand
The diagnosis of cirrhosis by high resolution ultrasound of the liver surface.
TLDR
US evaluation of the ventral contour of the liver was performed using a 7.5 MHz linear transducer in 100 patients with suspected liver disease and only reproducible diffuse ventral liver surface irregularities were considered as an objective US sign of cirrhosis. Expand
[Alcoholic and nonalcoholic steatohepatitis: the same disease! II. Management].
TLDR
It is recommended that coexisting metabolic alterations that are commonly observed in non-alcoholic steatohepatitis should also be treated in alcoholics, as well as weight reduction, physical exercise, improvement of insulin sensitivity and reduction of oxidative stress. Expand
Sampling variability on percutaneous liver biopsy.
Sampling variability of liver biopsy was determined in three consecutive biopsy specimens obtained from each of 118 patients immediately prior to autopsy. No sampling variability was found for fattyExpand
...
1
2
3
...