Circumventing cancer drug resistance in the era of personalized medicine.

@article{Garraway2012CircumventingCD,
  title={Circumventing cancer drug resistance in the era of personalized medicine.},
  author={Levi A. Garraway and Pasi Antero J{\"a}nne},
  journal={Cancer discovery},
  year={2012},
  volume={2 3},
  pages={
          214-26
        }
}
UNLABELLED All successful cancer therapies are limited by the development of drug resistance. The increase in the understanding of the molecular and biochemical bases of drug efficacy has also facilitated studies elucidating the mechanism(s) of drug resistance. Experimental approaches that can help predict the eventual clinical drug resistance, coupled with the evolution of systematic genomic and proteomic technologies, are rapidly identifying novel resistance mechanisms. In this review, we… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
SHOWING 1-10 OF 172 CITATIONS, ESTIMATED 55% COVERAGE

312 Citations

0204060'13'15'17'19
Citations per Year
Semantic Scholar estimates that this publication has 312 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 90 REFERENCES

Bone marrow stromasecreted cytokines protect JAK 2 ( V 617 F )mutated cells from the effects of a JAK 2 inhibitor

  • T Manshouri, Z Estrov, A Quintas-Cardama, J Burger, Y Zhang, A Livun
  • Cancer Res
  • 2011

Similar Papers

Loading similar papers…