Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus.

@article{Zinman1999CirculatingTN,
  title={Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus.},
  author={Bernard Zinman and Anthony J. G. Hanley and Stewart B Harris and Jeremy Kwan and Ivan George Fantus},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 1},
  pages={272-8}
}
Recent research suggests that tumor necrosis factor-alpha (TNF alpha) may play an important role in obesity-associated insulin resistance and diabetes. We studied the relationship between TNF alpha and the anthropometric and physiological variables associated with insulin resistance and diabetes in an isolated Native Canadian population with very high rates of type 2 diabetes mellitus (DM). A stratified random sample (n = 80) of participants was selected from a population-based survey designed… CONTINUE READING

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