Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications.

@article{Harouaka2014CirculatingTC,
  title={Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications.},
  author={Ramdane A. Harouaka and Zhigang Kang and Si-Yang Zheng and Liang Cao},
  journal={Pharmacology & therapeutics},
  year={2014},
  volume={141 2},
  pages={209-21}
}
Circulating tumor cells (CTCs) are rare cancer cells released from tumors into the bloodstream that are thought to have a key role in cancer metastasis. The presence of CTCs has been associated with worse prognosis in several major cancer types, including breast, prostate and colorectal cancer. There is considerable interest in CTC research and technologies for their potential use as cancer biomarkers that may enhance cancer diagnosis and prognosis, facilitate drug development, and improve the… CONTINUE READING
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