Circulating tumor cell interactions with macrophages: implications for biology and treatment.

@article{Hamilton2017CirculatingTC,
  title={Circulating tumor cell interactions with macrophages: implications for biology and treatment.},
  author={Gerhard Hamilton and Barbara Rath},
  journal={Translational lung cancer research},
  year={2017},
  volume={6 4},
  pages={418-430}
}
Cancer and metastasis are closely associated with inflammation. Macrophages are important effector cells in enhancing tumor proliferation, invasion and providing protection against the immune system. Despite advanced knowledge of tumor-macrophage interactions, the role of macrophages in emergence and invasion of circulating tumor cells (CTCs) is not known. A series of six CTC cell lines have been derived from blood of patients with extensive disease small cell lung cancer (ED-SCLC) in our lab… CONTINUE READING

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