Circulating serum miRNA (miR-367-3p, miR-371a-3p, miR-372-3p and miR-373-3p) as biomarkers in patients with testicular germ cell cancer.

@article{Syring2015CirculatingSM,
  title={Circulating serum miRNA (miR-367-3p, miR-371a-3p, miR-372-3p and miR-373-3p) as biomarkers in patients with testicular germ cell cancer.},
  author={I. Syring and J. Bartels and S. Holdenrieder and G. Kristiansen and S. M{\"u}ller and J. Ellinger},
  journal={The Journal of urology},
  year={2015},
  volume={193 1},
  pages={
          331-7
        }
}
PURPOSE Classic serum tumor markers (human chorionic gonadotropin, α1-fetoprotein and lactate dehydrogenase) have an important role in managing testicular germ cell tumor. Since only 60% of all patients with testicular germ cell tumor have elevations of these markers, there is a need for new biomarkers with greater sensitivity/specificity. miRNAs are deregulated in cancer and could serve as noninvasive serum biomarkers. We explored the role of serum miRNAs as a novel biomarker in patients with… Expand
Serum Levels of MicroRNA-371a-3p (M371 Test) as a New Biomarker of Testicular Germ Cell Tumors: Results of a Prospective Multicentric Study
  • K. Dieckmann, A. Radtke, +36 authors G. Belge
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2019
microRNA-371a-3p as informative biomarker for the follow-up of testicular germ cell cancer patients
Quantitative PCR Measurement of miR-371a-3p and miR-372-p Is Influenced by Hemolysis
MiR-371a-3p Serum Levels Are Increased in Recurrence of Testicular Germ Cell Tumor Patients
Serum levels of microRNA-371a-3p are not elevated in testicular tumours of non-germ cell origin
Differential expression of miRNAs in the seminal plasma and serum of testicular cancer patients
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