Circulating relaxin acts on subfornical organ neurons to stimulate water drinking in the rat.

@article{Sunn2002CirculatingRA,
  title={Circulating relaxin acts on subfornical organ neurons to stimulate water drinking in the rat.},
  author={Nana Sunn and Marcel Egli and Tanya C D Burazin and P R Burns and L M Colvill and Pamela J. Davern and Derek A. Denton and B J Oldfield and Richard S. Weisinger and Matthias Rauch and Herbert A. Schmid and M J Mckinley},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 3},
  pages={1701-6}
}
Relaxin, a peptide hormone secreted by the corpus luteum during pregnancy, exerts actions on reproductive tissues such as the pubic symphysis, uterus, and cervix. It may also influence body fluid balance by actions on the brain to stimulate thirst and vasopressin secretion. We mapped the sites in the brain that are activated by i.v. infusion of a dipsogenic dose of relaxin (25 microg/h) by immunohistochemically detecting Fos expression. Relaxin administration resulted in increased Fos… CONTINUE READING

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