Circulating regulatory T cells in "clinical" monoclonal B-cell lymphocytosis.

  title={Circulating regulatory T cells in "clinical" monoclonal B-cell lymphocytosis.},
  author={Giovanni D'Arena and Giuseppe Rossi and Maria Marta Minervini and Lucia Savino and Fiorella D'Auria and Luca Laurenti and Maria Ilaria Del Principe and Silvia Deaglio and Annalisa Biagi and Laura De Martino and Vincenzo De Feo and Teodora Statuto and Pellegrino Musto and Giovanni Del Poeta},
  journal={International journal of immunopathology and pharmacology},
  volume={24 4},
Regulatory T-cells (Tregs) constitute a small subset of cells involved in antitumour immunity and are generally increased in patients with chronic lymphocytic leukemia (CLL). No data is available on Tregs in monoclonal B-cell lymphocytosis (MBL), a disease entity characterized by less than 5000/microL circulating clonal B-cells in absence of other features of lymphoproliferative disorders. We used multicolour flow cytometry to evaluate the number of circulating Tregs in 56 patients with… CONTINUE READING