Circulating oxidized LDL: a biomarker and a pathogenic factor.

  title={Circulating oxidized LDL: a biomarker and a pathogenic factor.},
  author={Yasushi Ishigaki and Yoshitomo Oka and Hideki Katagiri},
  journal={Current opinion in lipidology},
  volume={20 5},
PURPOSE OF REVIEW Oxidized LDL (oxLDL) contributes to many atherogenic steps in the vascular wall, but the significance of oxLDL in circulating blood remains unclear. Recent progress in procedures for measuring both human and murine oxLDL has provided growing evidence of the importance of circulating oxLDL. RECENT FINDINGS Circulating oxLDL is elevated in patients with advanced atherosclerosis, such as coronary heart disease and ischemic stroke, and also reflects early atherosclerotic changes… CONTINUE READING
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