Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma.

@article{Bonini1996CirculatingNG,
  title={Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma.},
  author={Sergio Bonini and Alessandro Lambiase and Francesco Angelucci and Leonardo Magrini and Luigi Manni and Luigi Aloe},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 20},
  pages={10955-60}
}
Nerve growth factor (NGF) serum levels were measured in 49 patients with asthma and/or rhinoconjunctivitis and/or urticaria-angioedema. Clinical and biochemical parameters, such as bronchial reactivity, total and specific serum IgE levels, and circulating eosinophil cationic protein levels, were evaluated in relation to NGF values in asthma patients. NGF was significantly increased in the 42 allergic (skin-test- or radioallergosorbent-test-positive) subjects (49.7 +/- 28.8 pg/ml) versus the 18… CONTINUE READING