Circulating motilin, ghrelin, and GLP-1 and their correlations with gastric slow waves in patients with chronic kidney disease.

@article{Wu2017CirculatingMG,
  title={Circulating motilin, ghrelin, and GLP-1 and their correlations with gastric slow waves in patients with chronic kidney disease.},
  author={Gao-jue Wu and Xu-Dong Cai and Jie Xing and Guang-Hui Zhong and Jiande D. Z. Chen},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2017},
  volume={313 2},
  pages={R149-R157}
}
Patients with chronic kidney disease (CKD) commonly complain upper gastrointestinal (GI) symptoms, especially anorexia. Hemodialysis (HD) has been noted to improve GI symptoms; however, the underlying mechanisms are unclear. This study was designed 1) to study effects of HD on GI symptoms and gastric slow waves; and 2) to investigate possible roles of ghrelin and glucagon-like peptide-1 (GLP-1): the study recruited 13 healthy controls, 20 CKD patients without HD (CKD group), and 18 CKD patients… CONTINUE READING