Circulating monocytes from healthy individuals and COPD patients

  title={Circulating monocytes from healthy individuals and COPD patients},
  author={Ruta Aldonyte and Lennart T Jansson and Eeva Piitulainen and Sabina M. Janciauskiene},
  journal={Respiratory Research},
  pages={11 - 11}
BACKGROUND Chronic obstructive pulmonary disease (COPD) is characterized by incompletely reversible airflow obstruction associated with inflammation in which monocytes/macrophages are the predominant inflammatory cells. The only known genetic factor related to COPD is inherited PiZZ deficiency of alpha1-antitrypsin (AAT), an inhibitor of serine proteases. METHODS We investigated the basal and LPS-stimulated release of pro-inflammatory molecules from blood monocytes isolated from age and… CONTINUE READING
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