Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis.

@article{Shantsila2010CirculatingMI,
  title={Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis.},
  author={Eduard Shantsila and Pieter Willem Kamphuisen and Gregory Y. H. Lip},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2010},
  volume={8 11},
  pages={
          2358-68
        }
}
The complex and multifactorial nature of atherogenesis and development of atherothrombotic complications involves numerous interactions between various cell types inside the vascular wall (e.g. macrophages and smooth muscle cells) and in the blood (e.g. leukocytes and platelets). One relatively recent advance in this area is the discovery of circulating microparticles and their role in endothelial damage, platelet activation, hypercoagulability and regulation of inter-cellular interactions… CONTINUE READING
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