Circulating microparticles are elevated in carriers of factor V Leiden.

  title={Circulating microparticles are elevated in carriers of factor V Leiden.},
  author={Anoop Kumar Enjeti and Lisa F Lincz and Fiona E. Scorgie and Michael Seldon},
  journal={Thrombosis research},
  volume={126 3},
INTRODUCTION Microparticles (MP) are small membrane bound cellular particles that play an important role in thrombosis. This study was carried out to evaluate if increased numbers or procoagulant potential of circulating MP contribute to the heterogeneity in occurrence of thrombosis in heterozygotes carrying Factor V Leiden (FVL) mutation. METHODS Levels of circulating platelet (CD41a), endothelial (CD62e) as well as leukocyte (CD45) derived MP from 45 FVL heterozygous individuals were… CONTINUE READING


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