Circulating microRNAs in plasma of patients with oesophageal squamous cell carcinoma

@article{Komatsu2011CirculatingMI,
  title={Circulating microRNAs in plasma of patients with oesophageal squamous cell carcinoma},
  author={S. Komatsu and D. Ichikawa and H. Takeshita and M. Tsujiura and R. Morimura and H. Nagata and T. Kosuga and D. Iitaka and H. Konishi and A. Shiozaki and H. Fujiwara and K. Okamoto and E. Otsuji},
  journal={British Journal of Cancer},
  year={2011},
  volume={105},
  pages={104 - 111}
}
Background:Several recent studies demonstrated that microRNAs (miRNAs) are stably detectable in plasma/serum. We hypothesised that plasma miRNAs concentrations contributed to potential biomarkers in patients with oesophageal squamous cell carcinoma (ESCC).Methods:We selected three oncogenic miRNAs (miR-21, miR-184, miR-221) and one tumour suppressive miRNA (miR-375), which are frequently reported in squamous cell carcinoma, as candidate targets for this plasma miRNA assay. This study was… Expand
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