Circulating microRNAs as biomarkers for early detection of diffuse-type gastric cancer using a mouse model

Abstract

Background:Diffuse-type gastric cancer (DGC) exhibits rapid disease progression and a poor prognosis. There are no effective serum biomarkers for early detection of DGC. We have established an E-cadherin/p53 double conditional knockout (DCKO) mouse line that recapitulates human DGC morphologically and molecularly. In this study we tried to identify… (More)
DOI: 10.1038/bjc.2013.30

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