Circulating microRNA Signatures in Rodent Models of Pain

@article{Qureshi2015CirculatingMS,
  title={Circulating microRNA Signatures in Rodent Models of Pain},
  author={Rehman Qureshi and Yuzhen Tian and Marguerite K. McDonald and Kathryn E. Capasso and Sabrina R. Douglas and Ruby Y Gao and Irina A. Orlova and James E. Barrett and Seena K. Ajit and Ahmet Sacan},
  journal={Molecular Neurobiology},
  year={2015},
  volume={53},
  pages={3416-3427}
}
MicroRNAs (miRNAs) remain stable in circulation and have been identified as potential biomarkers for a variety of conditions. We report miRNA changes in blood from multiple rodent models of pain, including spinal nerve ligation and spared nerve injury models of neuropathic pain; a complete Freund’s adjuvant (CFA) model of inflammatory pain; and a chemotherapy-induced model of pain using the histone deacetylase inhibitor JNJ-26481585. The effect of celecoxib, a cyclooxygenase-2-selective… CONTINUE READING
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