Circulating microRNA-21 as a prognostic, biological marker in cholangiocarcinoma.

  title={Circulating microRNA-21 as a prognostic, biological marker in cholangiocarcinoma.},
  author={Chen-hai Liu and Qiang Huang and Zhi-Yuan Jin and Fang Tao Xie and Cheng-lin Zhu and Zhen Jiang Liu and Chao Wang},
  journal={Journal of cancer research and therapeutics},
  volume={14 1},
Aims The prognosis of cholangiocarcinoma (CCA) is generally poor because there is a lack of effective diagnostic tools including laboratory assessments and imageological examination. Therefore, a novel biological marker (biomarker) to effectively diagnose cancer is highly desirable in clinical. Previously, serum microRNAs as biomarkers of cancers have been reported. However, it was still unclear about the clinical significance of serum microRNA-21 (miR-21) expression levels for CCA. Materials… CONTINUE READING