Circulating miR-17-5p and miR-20a: molecular markers for gastric cancer.

  title={Circulating miR-17-5p and miR-20a: molecular markers for gastric cancer.},
  author={Mei Wang and Hongbing Gu and Sheng Wang and Hui Qian and Wei Zhu and Ling Zhang and Chonghui Zhao and Yang Tao and Wenrong Xu},
  journal={Molecular medicine reports},
  volume={5 6},
Circulating miR-17-5p and miR-20a (miR-17-5p/20a) have been demonstrated to be elevated in the plasma of gastric cancer patients. However, the clinical significance of the circulating levels of these microRNAs (miRNAs), the predictive power for prognosis and application for monitoring of chemotherapeutic effects remain unclear. To this end, we measured plasma miR-17-5p/20a levels in unpaired pre-operative (n=65), post-operative (n=16) and relapse (n=6) gastric cancer patient groups. The 3-year… CONTINUE READING
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