Circulating macrophage colony-stimulating factor is not reduced in malignant osteopetrosis.

@article{Orchard1992CirculatingMC,
  title={Circulating macrophage colony-stimulating factor is not reduced in malignant osteopetrosis.},
  author={P J Orchard and Niklas Dahl and Sharon Lea Aukerman and Bruce R Blazar and L. Lyndon Key},
  journal={Experimental hematology},
  year={1992},
  volume={20 1},
  pages={103-5}
}
Malignant osteopetrosis is a disorder characterized by a deficiency in osteoclast number or function. In one animal model of osteopetrosis, the op/op mouse, macrophage colony-stimulating factor (M-CSF) is absent, and the administration of M-CSF corrects the defects. We evaluated the serum of 13 patients with malignant osteopetrosis by an M-CSF… CONTINUE READING