Circulating levels of secretory type II phospholipase A(2) predict coronary events in patients with coronary artery disease.

@article{Kugiyama1999CirculatingLO,
  title={Circulating levels of secretory type II phospholipase A(2) predict coronary events in patients with coronary artery disease.},
  author={Kiyotaka Kugiyama and Yasutaka Ota and Keiji Takazoe and Yasushi Moriyama and Hiroaki Kawano and Yuji Miyao and Tomohiro Sakamoto and Hirofumi Soejima and Hisao Ogawa and Hiroshi Doi and Seigo Sugiyama and Hirofumi Yasue},
  journal={Circulation},
  year={1999},
  volume={100 12},
  pages={1280-4}
}
Background-The circulating levels of secretory nonpancreatic type II phospholipase A(2) (sPLA(2)) are increased in various chronic inflammatory diseases and the increase in the levels correlates with the disease severity. sPLA(2) may possibly play a role in atherogenesis and is highly expressed in atherosclerotic arterial walls that are known to have inflammatory features. Thus, this study prospectively examined whether circulating levels of sPLA(2) may have a significant risk and prognostic… CONTINUE READING
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