Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy.

@article{Huzen2011CirculatingLA,
  title={Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy.},
  author={Jardi Huzen and Wouter Peeters and Rudolf A de Boer and Frans L Moll and Liza S. M. Wong and Veryan Codd and Dominique P. V. de Kleijn and Bart JGL de Smet and Dirk Jan van Veldhuisen and Nilesh J. Samani and Wiek H van Gilst and G. Pasterkamp and Pim van der Harst},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2011},
  volume={31 5},
  pages={1219-25}
}
OBJECTIVE Shorter leukocyte telomeres are associated with atherosclerosis and predict future heart disease. The goal of the present study was to determine whether leukocyte telomere length is related to atherosclerotic plaque telomere length and whether it is associated with plaque characteristics or recurrence of disease. METHODS AND RESULTS Telomere length was measured by real-time quantitative polymerase chain reaction in atherosclerotic plaques and leukocytes in patients with carotid… CONTINUE READING

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