Circulating irisin in relation to insulin resistance and the metabolic syndrome.

  title={Circulating irisin in relation to insulin resistance and the metabolic syndrome.},
  author={Kyung Hee Park and Lesya Zaichenko and Mary T Brinkoetter and Bindiya Thakkar and Ayse Sahin-Efe and Kyoung Eun Joung and Michael A. Tsoukas and Eleni V Geladari and Joo Young Huh and Fadime Dincer and Cynthia R Davis and Judith A. Crowell and Christos Socrates Mantzoros},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={98 12},
CONTEXT Irisin, a recently identified hormone, has been proposed to regulate energy homeostasis and obesity in mice. Whether irisin levels are associated with risk of the metabolic syndrome (MetS), cardiometabolic variables, and cardiovascular disease (CVD) risk in humans remains unknown. OBJECTIVE Our objective was to assess the associations between baseline serum irisin levels and MetS, cardiometabolic variables, and CVD risk. DESIGN, SETTING, AND SUBJECTS We conducted a comparative cross… CONTINUE READING
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