Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans.

@article{Cannon1992CirculatingIB,
  title={Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans.},
  author={Joseph G. Cannon and Joseph S. Friedberg and Jeffrey Gelfand and Ronald G. Tompkins and John F. Burke and Charles A Dinarello},
  journal={Critical care medicine},
  year={1992},
  volume={20 10},
  pages={1414-9}
}
OBJECTIVES To measure plasma interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF alpha) concentrations after burn injury and to determine if these concentrations relate to clinical status. DESIGN Prospective assessment. SETTING Hospital burn unit. PATIENTS Thirty-one patients with second- or third-degree burns, covering 10% to 95% of body surface area. MEASUREMENTS AND MAIN RESULTS Initial concentrations of IL-1 beta were increased (mean 188 +/- 31 pg/mL), and the… CONTINUE READING

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