Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease.

@article{Achberger2014CirculatingIC,
  title={Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease.},
  author={Susan Achberger and Winthrop Aldrich and Raymond R. Tubbs and John W. Crabb and Arun Singh and Pierre L Triozzi},
  journal={Molecular immunology},
  year={2014},
  volume={58 2},
  pages={
          182-6
        }
}
BACKGROUND The immune response has been implicated in the control of uveal melanoma progression. Epigenetic mechanisms mediated by specific microRNAs (miRs) regulate immune responses. METHODS Blood was drawn from six patients with uveal melanoma followed from diagnosis, at which time there was no clinical or radiographic evidence of metastasis, until metastasis manifested. Circulating T cell, natural killer (NK), natural killer T (NKT), and myeloid suppressor cell populations were assessed by… CONTINUE READING
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