Circulating hepcidin in the crossroads of anemia and inflammation associated with rheumatoid arthritis.

  title={Circulating hepcidin in the crossroads of anemia and inflammation associated with rheumatoid arthritis.},
  author={Mehmet Derya Demirağ and Şeminur Haznedaroğlu and Banu Sancak and Ceyla Konca and Ozlem Gulbahar and Mehmet Akif Ozturk and Berna Goker},
  journal={Internal medicine},
  volume={48 6},
OBJECTIVE To investigate the role of circulating hepcidin, which is a homeostatic regulator of iron metabolism and a mediator of inflammation, in anemia associated with rheumatoid arthritis. METHODS Forty patients with rheumatoid arthritis (19 with anemia and 21 without anemia), 12 patients with iron deficiency anemia and 14 healthy adults were studied. Serum hepcidin levels were analyzed with hepcidin prohormone solid phase enzyme-linked immunosorbent assay. RESULTS The mean serum hepcidin… CONTINUE READING


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