Circulating fatty acid profiles in response to three levels of dietary omega-3 fatty acid supplementation in horses.

@article{King2008CirculatingFA,
  title={Circulating fatty acid profiles in response to three levels of dietary omega-3 fatty acid supplementation in horses.},
  author={S. S. King and Amer A. AbuGhazaleh and Stephen K. Webel and K. L. Jones},
  journal={Journal of animal science},
  year={2008},
  volume={86 5},
  pages={
          1114-23
        }
}
Fatty acids of the n-3 type confer health benefits to humans and other species. Their importance to equine physiology could include improved exercise tolerance, decreased inflammation, and improved reproductive function. The circulating fatty acid profile and the acquisition and washout of fatty acids in response to n-3 supplementation were determined for horses in the current study. A fatty acid supplement high in eicosapentaenoic (EPA) and docosahexaenoic (DHA) acid was fed to deliver EPA… 
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TLDR
Diet did not affect serum CPII or CS-846 nor synovial white blood cell count, total protein, and specific gravity, but plasma eicosapentaenoic Acid and docosahexaenoic acid increased in response to supplementation.
Omega-3 Fatty Acid Supplementation Affects Selected Phospholipids in Peripheral White Blood Cells and in Plasma of Full-Sized and Miniature Mares
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Data indicated a low to moderate relationship between the dietary linseed-based oil supplementation studied and circulating and follicular fluid polyunsaturated fatty acids contents in mares.
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DHA and EPA supplementation results in augmented storage pools of ω-3 essential fatty acids in SF and surfactant GPC, which has the potential to improve the ability of anti-inflammatory mechanisms to resolve inflammatory pathways in these critical compartments involved in arthritis and asthma.
Omega‐3 Fatty Acid Supplementation Provides an Additional Benefit to a Low‐Dust Diet in the Management of Horses with Chronic Lower Airway Inflammatory Disease
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Feeding horses with RAO and IAD a PUFA supplement containing 1.5–3 g DHA for 2 months provides an additional benefit to low‐dust diet.
Effect of dietary omega-3 fatty acid source on plasma and red blood cell membrane composition and immune function in yearling horses.
TLDR
Across treatments, the peak increase in skin thickness was observed 4 to 8 h after PHA injection, and fish oil had a greater impact on plasma and RBC n-3 FA content than did flaxseed, however, supplementing horses with both fish oil and flax Seed resulted in a more pronounced early inflammatory response to PHA injections as compared with nonsupplemented horses.
Dietary supplementation of conjugated linoleic acid in horses increases plasma conjugated linoleic acid and decreases plasma arachidonic acid but does not alter body fat.
TLDR
In an equine model, dietary CLA increases circulating concentrations of supplemented CLA isomers and decreases circulating C20:4, the major substrate of cyclooxygenase (COX) II inflammatory pathway.
Effects of two different dietary sources of long chain omega-3, highly unsaturated fatty acids on incorporation into the plasma, red blood cell, and skeletal muscle in horses.
TLDR
This is the first study to demonstrate that dietary fatty acid supplementation will affect muscle fatty acid composition in horses and incorporation of n-3 LCHUFA into blood and muscle depends directly on dietary supply of specific fatty acids.
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