Circulating endothelial precursors: mystery, reality, and promise.

  title={Circulating endothelial precursors: mystery, reality, and promise.},
  author={Shahin Rafii},
  journal={The Journal of clinical investigation},
  volume={105 1},
  • Shahin Rafii
  • Published 2000 in The Journal of clinical investigation
physiological processes such as wound healing and tumor growth require endothelial migration, proliferation, and stabilization, a process referred to as angiogenesis. Initial phases of angiogenesis involve the recruitment of endothelial cells to the site of injury or to the tumor vascular bed. Two possible sources of endothelialization are (a) migration and co-option (1, 2) of preexisting vascular wall endothelial cells and (b) recruitment of endothelial precursor cells from the circulation… CONTINUE READING


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