Circulating endothelial cells in vascular disorders: new insights into an old concept.

@article{DignatGeorge2000CirculatingEC,
  title={Circulating endothelial cells in vascular disorders: new insights into an old concept.},
  author={Françoise Dignat-George and Jos{\'e} Sampol},
  journal={European journal of haematology},
  year={2000},
  volume={65 4},
  pages={215-20}
}
The endothelial contribution to vascular disorders has been widely documented in experimental models. However, its implication in human pathology is difficult to investigate, owing to the paucity of noninvasive methods and of specific endothelial markers. The enumeration of circulating endothelial cells (CEC) released in peripheral blood after vascular injury represents a direct exploration of the endothelium. For this purpose, we have produced a monoclonal antibody (S-Endo 1), which recognizes… CONTINUE READING

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