Circulating endothelial cells as biomarkers in clinical oncology.

  title={Circulating endothelial cells as biomarkers in clinical oncology.},
  author={Patrizia Mancuso and Francesco Bertolini},
  journal={Microvascular research},
  volume={79 3},
Circulating endothelial cells (CECs) and circulating endothelial progenitors (CEPs) play a different role in cancer development, acting as possible markers of vascular turnover/damage (CECs) and vasculogenesis (CEPs). Preclinical and clinical data suggest that CEC enumeration might be useful to define the best treatment option for patients who are candidate to anti-angiogenic therapy, while CEPs seem to have a "catalytic" role in different steps of cancer progression and recurrence after… CONTINUE READING

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