Circulating endothelial cells as a novel marker of angiogenesis.

@article{Mancuso2003CirculatingEC,
  title={Circulating endothelial cells as a novel marker of angiogenesis.},
  author={Patrizia Mancuso and Angelica Calleri and Cristina Cassi and Alberto Gobbi and Manuela Capillo and Giancarlo Pruneri and Giovanni Martinelli and Francesco Bertolini},
  journal={Advances in experimental medicine and biology},
  year={2003},
  volume={522},
  pages={
          83-97
        }
}
Measurement of tumor angiogenesis to predict and/or to assess the efficacy of antiangiogenic therapies is mainly based on the evaluation of microvessel density (MVD). We developed a novel flow cytometry procedure to measure circulating endothelial cells (CECs) and circulating endothelial cells progenitors (CECPs) in either preclinical and clinical studies. Preclinical studies were performed on an animal model of human lymphoma. A trend toward higher CECs values was observed on day 7 and 14… CONTINUE READING

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Circulating endothelial cells: a novel marker of endothelial damage.

  • Clinica chimica acta; international journal of clinical chemistry
  • 2006
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