Circulating endothelial cells and vascular cell adhesion molecule-1 correlates with severity of regurgitation lesion and heart failure in rheumatic heart disease

  title={Circulating endothelial cells and vascular cell adhesion molecule-1 correlates with severity of regurgitation lesion and heart failure in rheumatic heart disease},
  author={Wulan Sasmeita and Renny Suwarniaty and Loeki Enggar Fitri and Mohammad Saifur Rohman and Siti Lintang Kawuryan},
  journal={Journal of Experimental and Integrative Medicine},
Objective: This study aims to determine the correlation of vascular cell adhesion molecule-1 (VCAM-1) and circulating endothelial cells (CEC) with cardiac valves lesion severity and heart failure (HF) in rheumatic heart disease (RHD). Methods: A cross-sectional observational study using human peripheral blood samples of 36 children aged 6 to14 years old, divided into two groups: 18 RHD patients and 18 healthy controls group. The expression of CECs and VCAM-1 on CECs was investigated by using… 

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