Circulating dipeptidyl peptidase-4 activity is associated with diabetic retinopathy in type 1 diabetic patients.

@article{Blaslov2015CirculatingDP,
  title={Circulating dipeptidyl peptidase-4 activity is associated with diabetic retinopathy in type 1 diabetic patients.},
  author={Kristina Blaslov and Tomislav Bulum and Lea Smir{\vc}i{\'c} Duvnjak},
  journal={European journal of ophthalmology},
  year={2015},
  volume={25 4},
  pages={328-32}
}
PURPOSE Diabetic retinopathy (DR) is the most frequent complication among patients with type 1 diabetes mellitus (T1DM). Dipeptidyl peptidase-4 (DPP4) is a protease with elevated activity in patients with T1DM. Several studies indicate that DPP4 inhibitors might have beneficial effect on nonproliferative retinopathy (NPR) development as well as on its progression to proliferative retinopathy (PR). We aimed to explore the relationship between serum DPP4 activity and DR in patients with T1DM… CONTINUE READING