Circulating cytokine levels and antibody responses to human Schistosoma haematobium: IL-5 and IL-10 levels depend upon age and infection status

@inproceedings{Milner2010CirculatingCL,
  title={Circulating cytokine levels and antibody responses to human Schistosoma haematobium: IL-5 and IL-10 levels depend upon age and infection status},
  author={Teresa A Milner and Liam Reilly and Norman Nausch and Nicholas Midzi and Takafira Mduluza and Rory J Maizels and Francisca Mutapi},
  booktitle={Parasite immunology},
  year={2010}
}
Experimental schistosome infections induce strong parasite-specific Th2 responses. This study aims to relate human systemic cytokine and antibody levels to schistosome infection levels and history. Levels of anti-Schistosoma haematobium antibodies (directed against crude cercariae, egg and adult worm antigens) and plasma cytokines (IFN-γ, IL-2, IL-4, IL-5, IL-10, IL-13, IL-17, IL-21, and IL-23) were measured by ELISA in 227 Zimbabweans (6-60 years old) in a schistosome-endemic area and related… CONTINUE READING

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