Circulating concentrations of nocturnal leptin, growth hormone, and insulin-like growth factor-I increase before the onset of puberty in agonadal male monkeys: potential signals for the initiation of puberty.

@article{Suter2000CirculatingCO,
  title={Circulating concentrations of nocturnal leptin, growth hormone, and insulin-like growth factor-I increase before the onset of puberty in agonadal male monkeys: potential signals for the initiation of puberty.},
  author={K. J. Suter and Clifford R Pohl and M Eilidh Wilson},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2000},
  volume={85 2},
  pages={808-14}
}
The factor(s) responsible for initiating the developmental increase in nocturnal gonadotropin-releasing hormone secretion, defining the onset of puberty, are not known. Although signals regulating prepubertal growth seem to be obvious candidates to control such a process, it is unclear whether prepubertal alterations occur in these growth-related factors… CONTINUE READING