Circulating cardiac-specific autoantibodies as markers of autoimmunity in clinical and biopsy-proven myocarditis. The Myocarditis Treatment Trial Investigators.

@article{Caforio1997CirculatingCA,
  title={Circulating cardiac-specific autoantibodies as markers of autoimmunity in clinical and biopsy-proven myocarditis. The Myocarditis Treatment Trial Investigators.},
  author={Alida Linda Caforio and Jonathan H Goldman and Aldwyn J Haven and Khurrum M. Baig and Luciano Dalla Libera and William J. McKenna},
  journal={European heart journal},
  year={1997},
  volume={18 2},
  pages={270-5}
}
AIM Myocarditis and dilated cardiomyopathy may be phases of an organ-specific autoimmune disease of the myocardium. To provide evidence for autoimmune involvement in myocarditis, cardiac autoantibodies were detected in patient sera from the Myocarditis Treatment Trial. METHODS AND RESULTS Cardiac antibody status was assessed by indirect immunofluorescence and by anti-alpha-myosin enzyme-linked immunosorbent assay in 53 patients from the Myocarditis Treatment Trial (35 males, aged 42 +/- 15… CONTINUE READING