Circulating branched-chain amino acids in children with obstructive sleep apnea.

@article{Barcelo2017CirculatingBA,
  title={Circulating branched-chain amino acids in children with obstructive sleep apnea.},
  author={A. Garau Barcelo and Josep Miquel Bauç{\`a} and Jos{\'e} Antonio Pe{\~n}a-Zarza and Daniel Morell-Garcia and Aina M. Ya{\~n}ez and Gerardo Alfonso Escalante P{\'e}rez and Javier Jos{\'e} Goikoetxea Pi{\'e}rola and Nuria Toledo and M{\'o}nica de la Pe{\~n}a},
  journal={Pediatric pulmonology},
  year={2017},
  volume={52 8},
  pages={
          1085-1091
        }
}
INTRODUCTION The effects of obstructive sleep apnea (OSA) on the metabolic system are not well understood, especially in children. Recent studies have provided evidence of the modulation of insulin action by branched-chain amino acids (BCAAs) and suggested novel mechanistic relationships between glucose and amino acid metabolic pathways. We hypothesized that plasma BCAA levels may serve as biomarkers of insulin resistance and metabolic dysfunction in children with OSA. METHODS A… CONTINUE READING
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