Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

@inproceedings{Sheinerman2017CirculatingBM,
  title={Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases},
  author={Kira S. Sheinerman and Jon B. Toledo and Vladimir G. Tsivinsky and David J Irwin and Murray Grossman and Daniel J. Weintraub and Howard I. Hurtig and Alice S Chen-Plotkin and David A. Wolk and L. F. McCluskey and L. B. Elman and John Q. Trojanowski and Samuil R Umansky},
  booktitle={Alzheimer's Research & Therapy},
  year={2017}
}
BackgroundMinimally invasive specific biomarkers of neurodegenerative diseases (NDs) would facilitate patient selection and disease progression monitoring. We describe the assessment of circulating brain-enriched microRNAs as potential biomarkers for Alzheimer’s disease (AD), frontotemporal dementia (FTD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS).MethodsIn this case-control study, the plasma samples were collected from 250 research participants with a clinical diagnosis… CONTINUE READING
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