Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway.

Abstract

Previous studies demonstrated the existence of osteoblastic cells in circulating blood. Recently, we reported that osteoblast progenitor cells (OPCs) in circulation originated from bone marrow and contributed to the formation of ectopic bone induced by implantation of a bone morphogenetic protein (BMP)-2-containing collagen pellet in mouse muscular tissue… (More)

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@article{Otsuru2008CirculatingBM, title={Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway.}, author={Satoru Otsuru and Katsuto Tamai and Takehiko Yamazaki and Hideki Yoshikawa and Yasufumi Kaneda}, journal={Stem cells}, year={2008}, volume={26 1}, pages={223-34} }