Circulating apoptotic and necrotic cell death markers in patients with acute liver injury.

@article{Craig2011CirculatingAA,
  title={Circulating apoptotic and necrotic cell death markers in patients with acute liver injury.},
  author={Darren G N Craig and Patricia Lee and Elizabeth A Pryde and Gail Susan Masterton and P C Hayes and Kenneth James Simpson},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2011},
  volume={31 8},
  pages={1127-36}
}
BACKGROUND The host response to cell death underpins the immune activation that follows acute liver injury, and measurement of circulating cell death markers could therefore aid prognostication following paracetamol overdose. Nucleosomes, formed during apoptosis, can complex with high-mobility group box 1 (HMGB1) protein and may play a pathogenic role in liver injury. AIMS To explore the levels and prognostic significance of nucleosomes, HMGB1, and other cell death markers following acute… CONTINUE READING
30 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Similar Papers

Loading similar papers…