Circulating angiogenic modulatory factors predict survival and functional class in pulmonary arterial hypertension

@inproceedings{Malhotra2013CirculatingAM,
  title={Circulating angiogenic modulatory factors predict survival and functional class in pulmonary arterial hypertension},
  author={Rajeev Kumar Malhotra and Samuel D Paskin-Flerlage and Roham T. Zamanian and Patrick Zimmerman and Jonathan W. Schmidt and Donna Y. Deng and M Elaine Southwood and Robert T Spencer and Carol S C Lai and William Parker and Richard N. Channick and Nicholas W Morrell and Charles Gregory Elliott and Paul B Yu},
  booktitle={Pulmonary circulation},
  year={2013}
}
The diagnosis of pulmonary arterial hypertension (PAH) is frequently delayed. We hypothesized that circulating angiogenic modulatory protein levels might correspond with vascular remodeling activity and serve as sensitive biomarkers of PAH. Levels of soluble endoglin (sEng), soluble vascular endothelial growth factor receptor-1 (sVEGFR1), N-terminal brain natriuretic peptide (NT-proBNP), C-reactive protein (CRP), and other biomarkers were measured in peripheral blood from 97 PAH patients, 16… CONTINUE READING
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