Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2.

@article{Brubaker1997CirculatingAT,
  title={Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2.},
  author={Patricia L Brubaker and Anna E. Crivici and Angelo A. Izzo and Paul R. Ehrlich and Chih Heng Tsai and Daniel J Drucker},
  journal={Endocrinology},
  year={1997},
  volume={138 11},
  pages={
          4837-43
        }
}
Glucagon-like peptide-2 (GLP-2) has recently been identified as a stimulator of intestinal epithelial growth, prompting the development of RIA and HPLC methodologies to study this peptide in more detail. A GLP-2-specific antiserum (UTTH-7) was developed that recognizes amino acids 25-30 of human and rat GLP-2-(1-33). UTTH-7 cross-reacts with N- and C-terminally modified forms of GLP-2, proglucagon, and the major proglucagon fragment. Analysis of rat ileal extracts demonstrated the presence of… CONTINUE READING

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