Circulating and disseminated tumor cells in the management of breast cancer.

  title={Circulating and disseminated tumor cells in the management of breast cancer.},
  author={Jeffrey S. Ross and Elzbieta A Slodkowska},
  journal={American journal of clinical pathology},
  volume={132 2},
Despite the advances in early detection and treatment of cancer, patients continue to die of the disease even when they seek care at an early stage. For patients with breast cancer, it is now possible to detect circulating tumor cells (CTCs) in the bloodstream and disseminated tumor cells (DTCs) in the bone marrow by using immunocytochemical and molecular methods. CTCs and DTCs have been found to share similar genotypic and phenotypic characteristics with so-called breast cancer stem cells, a… CONTINUE READING

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