Circulating adiponectin and leptin in relation to myelodysplastic syndrome: a case-control study.

@article{Dalamaga2007CirculatingAA,
  title={Circulating adiponectin and leptin in relation to myelodysplastic syndrome: a case-control study.},
  author={Maria Dalamaga and Athina Nikolaidou and Konstantinos Karmaniolas and Alex Hsi and John P Chamberland and Amalia Dionyssiou-Asteriou and Christos Socrates Mantzoros},
  journal={Oncology},
  year={2007},
  volume={73 1-2},
  pages={26-32}
}
OBJECTIVE Adiponectin plays a protective role in several malignancies, including myeloblastic leukemia, whereas leptin may increase the proliferation of progenitor cells and may stimulate leukemic cell growth in vitro. We investigated the role of adiponectin and leptin levels in the etiopathogenesis of myelodysplastic syndromes (MDS), a preleukemic condition with increasing incidence which has recently been associated with obesity. METHODS In a case-control study, 101 cases with incident… CONTINUE READING