Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training.

@article{Blher2006CirculatingAA,
  title={Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training.},
  author={Matthias Bl{\"u}her and John W Bullen and Jennifer H. Lee and Susan Kralisch and Mathias Fasshauer and Nora Kl{\"o}ting and Josef Niebauer and Michael R. Sch{\"o}n and Catherine J. Williams and Christos Socrates Mantzoros},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 6},
  pages={2310-6}
}
CONTEXT Adiponectin, an adipocyte-secreted hormone, is associated with insulin resistance and the metabolic syndrome. OBJECTIVE The physiological regulation of circulating adiponectin levels and mRNA expression of its receptors (AdipoR1 and AdipoR2) in skeletal muscle remains to be fully elucidated. DESIGN/PATIENTS We assessed circulating adiponectin and AdipoR1/R2 mRNA expression in human skeletal muscle in a cross-sectional study of 140 subjects with normal or impaired glucose tolerance… CONTINUE READING

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